Clozapine treatment reverses dizocilpine-induced deficits of pre-pulse inhibition of tactile startle response
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Clozapine treatment reverses dizocilpine-induced deficits of pre-pulse inhibition of tactile startle response.
Pre-pulse inhibition (PPI) is a phenomenon of neurobehavioral plasticity in which the motor response to a startling sensory stimulus is inhibited by a preceding sensory stimulus of a lower intensity. The current experiment used tactile startle rather than acoustic startle to determine the generality of PPI across sensory modalities. PPI is easily modeled in experimental animals and serves as a ...
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ژورنال
عنوان ژورنال: Pharmacology Biochemistry and Behavior
سال: 2007
ISSN: 0091-3057
DOI: 10.1016/j.pbb.2007.02.005